Peanut allergy: sublingual immunotherapy for children

Peanut allergy: sublingual immunotherapy for children

The PEANUTS SLIT (sublingual immunotherapy) method is to administer the medication as a small amount of liquid under the tongue, rather than habituating the allergy patient by adding a little peanut flour.

A “little piece” of peanut protein is absorbed under the tongue

the study, a 3-year clinical trial, supported by the National Institutes of Health, was conducted among 50 young children with peanut allergy, ages 1 to 4 years and assigned to receive either 4 mg of sublingual immunotherapy or a placebo. The analysis provides the first evidence of the safety and effectiveness of sublingual immunotherapy for peanut allergy in children ages 1 to 4 years. It is possible to cure peanut allergy after just 3 months of this immunotherapy.

  • Specifically, sublingual immunotherapy can be very effective in treating young children with peanut allergies.
  • At the end of treatment, approximately 80% of the young participants treated were able to tolerate 15 peanuts without developing any allergic symptoms;
  • Remission of peanut allergy appears to be possible after this sublingual immunotherapy, as observed in some participating children;
  • 63% of participants maintained this situation 3 months after stopping treatment.

Together, these results show that early intervention using immunotherapy for peanut allergy is promising and merits further investigation. Lead author Dr. Edwin Kim, MD, associate professor of pediatrics at UNC, comments on these findings: “We were looking to prove the treatment was effective, and what we found was even better:

The observed levels of desensitization turned out to be higher than expected

and are comparable to levels expected with standard oral immunotherapy. In addition, 60% of children remained protected three months after stopping treatment.

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One of the strengths of the sublingual immunotherapy approach is its overall safety And ease of management. Standard immunotherapy can actually cause serious reactions that require emergency treatment. It remains necessary to develop treatments for allergies with more manageable side effects.

Peanut slit It may be a good option to consider because it can provide similar levels of protection while being safer and easier to administer. Peanut allergy remains one of the most common types of food allergies. The early introduction of peanuts means that peanut allergy can be diagnosed at an increasingly younger age, making it extremely important to develop safe and effective treatments to prevent allergic reactions in these young people.

With the newer sublingual immunotherapy, the most common side effect is mouth itching. Treatments that can protect children from allergies while being safe and convenient for families

It can change lives and restore quality for children and parents alike.

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About the Author: Irene Alves

"Bacon ninja. Guru do álcool. Explorador orgulhoso. Ávido entusiasta da cultura pop."

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